http://malecontraceptives.org/methods/risug.php
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The first clinical trial of RISUG determined that an injection of 60 milligrams is the therapeutic dose (Guha 1993). The men who participated in that first trial have had RISUG implanted for 15 years and counting with no complications. The Phase II clinical trial volunteers have now been using RISUG for more than ten years. When RISUG was properly implanted, no pregnancies occurred during the 1-3 years of the study (Guha 1997), and informal follow ups with the volunteers have confirmed no pregnancies since. It's possible that smaller doses could provide shorter periods of contraception.
The compound can be injected using a no-scalpel procedure into the vasa deferentia, where it coats the walls within a matter of minutes. Practitioners of no-scalpel vasectomy should be able to adopt the technique relatively easily. Less skilled practitioners should be able to inject the compound after making a tiny incision that can be closed with one suture. Either technique would be an outpatient procedure completed within 15 minutes.
Once injected, the compound is anchored to the tiny folds on the inner surface of the vasa deferentia within 72 hours.
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